OncoLink at ASCO 1999: Monday, May 17

Combination Chemotherapy Regimen Yields Impressive Results in Late-Stage Prostate Cancer Atlanta, GA, May 17, 1999 -- The chemotherapeutic taxane agent docetaxel, combined with the nitrogen mustard estramustine phosphate and low dose hydrocortisone, appears to be a promising treatment for men with an advanced form of prostate cancer,...
PET Scans More Effective than Standard Technique at Accurately Staging Lung Cancer Classic "TNM" staging in lung cancer (an assessment of primary Tumor, regional lymph Node involvement, distant Metastasis) has only been partially effective at accurately predicting patient survival. Now, researchers at the University Hospital...
Preliminary Results of High-Dose Chemotherapy in Primary Breast Cancer Show Equivalency to Intermediate-Dose Treatment; 3 Years of Additional Follow-up Required 783 women with primary breast cancer that has spread to 10 or more lymph nodes under the arm were randomized to receive either high-dose chemotherapy (cyclophosphamide, cisplatin and BCNU) with bone marrow and peripheral blood stem cell support,...
Scandinavian Study Finds No Overall Survival Benefit to High-Dose Chemotherapy in Primary Breast Cancer A randomized Scandinavian study of 525 women with high-risk breast cancer, conducted over a four year period betwen 1994-1998 at a constant inclusion rate, indicates that there is no overall benefit to high-dose chemotherapy with bone marrow stem...
South African Study Finds Survival Benefit to High-Dose Chemotherapy in Primary Breast Cancer UPDATE: The data from this study have since been called into question. For more information concerning this, please consult: OncoLink NCI/PDQ: Misconduct Suspected in South African Breast Cancer Study. A South African study of 154 women with...
Soy Remedy Not Effective for Hot Flashes with Breast Cancer Researchers have found that a soy phytoestrogen preparation was ineffective for diminishing hot flashes in breast cancer survivors. This is despite soy phytoestrogen being touted by some to be helpful for diminishing hot flashes. Charles Loprinzi,...
Stem Cells May be Engineered to Resist Toxic Effects of Chemotherapy A research team led by the National Cancer Institute has taken the first steps toward making bone marrow stem cells resistant to the toxic effects of chemotherapy. Such an advance could potentially allow patients to undergo multiple rounds of...
Study of High-Dose Chemotherapy in Metastatic Breast Cancer Finds No Survival Benefit Analysis of data as of March 31, 1999, from the largest randomized trial of high-dose chemotherapy with stem cell transplant in the treatment of responding metastatic breast cancer has shown no significant difference in overall survival or...