OncoLink Cancer Treatment and Resources

Wednesday, October 31 2007

Includes scientific highlights from the breast, pancreatic, lung, sarcoma, esophagus, and prostate cancer sessions as well as patient friendly summaries of key presentations.

A Phase II Study of a Paclitaxel Based Chemoradiation Regimen With Selective Surgical Salvage for Resectable Locoregionally Advanced Esophageal Cancer: Initial Reporting of RTOG 0246
Presenter: Stephen Swisher, MDPresenter's Affiliation: MD Anderson Cancer CenterType of Session: ScientificBackground Prior studies (RTOG 8501) have demonstrated that chemoradiation is more effective than radiation alone in the treatment of...
Chest Wall Radiation Alone for Breast Cancer Patients With 1-3 Positive Lymph Nodes Treated by Mastectomy
Presenter: Shannon M. MacDonald, MDPresenter's Affiliation: Massachusetts General HospitalType of Session: ScientificBackground Numerous studies have demonstrated that the administration of adjuvant comprehensive postmastectomy radiation, which...
Definitive Results of the French FFCE-SFRO 2000-01 Study: Phase III Trial Comparing Chemoradiotherapy (Cisplating and Infusional 5-FU) Followed by Gemcitabine vs. Gemcitabine Alone in Patients with Locally Advanced Non Metastatic Pancreatic Cancer
Presenter: C.H. Crane substituting for F. MornexPresenter's Affiliation: Centre Hospitalier Lyon Sud, Lyon Pierre Benite, FranceType of Session: ScientificBackground Pancreatic cancer is the fourth most common malignancy in the United States,...
Impact of Postoperative Radiation Therapy on Postmastectomy Breast Reconstruction
Presenter: L.C. KeilerPresenter's Affiliation: University Hospital of Cleveland, Cleveland, OHType of Session: ScientificBackground Despite improvements in early-detection of breast cancer, many patients still present with disease requiring...
Inhibition of mTOR Radiosensitizes Soft Tissue Sarcoma and Tumor Vascualture
Presenter: James Murphy, MDPresenter's Affiliation: University of MichiganType of Session: ScientificBackground Rapamycin is an FDA approved immunosuppressant used in organ transplant, especially renal. It was derived from a soil sample...
Neurocognitive Impact of Whole Brain Radiation on Patients With Brain Metastases: Secondary Analysis of RTOG BR-0018
Presenter: Young Kwok, MDPresenter's Affiliation: University of Maryland Medical CenterType of Session: ScientificBackground In studies involving the treatment of patients with brain metastases, survival and time to progression may not fully...
Outcome After Stereotactic Radiotherapy in 'High-Risk' Patients With Stage I Non-small Cell Lung Cancer (NSCLC)
Presenter: F. J. LagerwaardPresenter's Affiliation: VU University Medical Center, Amsterdam, The NetherlandsType of Session: ScientificBackground Surgical treatment with lobectomy or pneumonectomy is recognized as the optimal treatment for...
Percent Necrosis in Extremity Soft Tissue Sarcoma After Preoperative Radiation Alone Versus Preoperative Radiation and Chemotherapy
Presenter: Karl Haglund MD, PhDPresenter's Affiliation: Massachusetts General HospitalType of Session: ScientificBackground Prior studies have found that treatment related necrosis is a prognostic marker in bone sarcomas. Retrospective...
Prospective Trial of Individual Optimal Positioning (Prone Versus Supine) for Whole Breast Radiotherapy: Results of the First 168 Patients
Presenter: Silvia C. Formenti, MDPresenter's Affiliation: New York University Medical CenterType of Session: ScientificBackground External beam radiation therapy as part of breast conservation therapy for early stage breast cancer has...
Statin Use and Clinical Outcomes after High-Dose Radiotherapy for Prostate Cancer
Presenter: M. ZelefskyPresenter's Affiliation: Memorial Sloan Kettering Cancer Center, New York, NYType of Session: ScientificBackground Clinical and laboratory work has suggested that 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors,...
Toxicity Analysis of RTOG 0236 Using Stereotactic Body Radiotherapy to Treat Medically Inoperable Early Stage Lung Cancer Patients
Presenter: Robert Timmerman, MDPresenter's Affiliation: University of Texas SouthwesternType of Session: ScientificBackground The treatment of patients with non-small cell lung cancer (NSCLC) who are unable to undergo surgery can be very...
Update of the Results of the Dutch Multicenter Dose Escalation Trial of Radiotherapy for Localized Prostate Cancer
Presenter: Abrahim Al-Mamgani, MDPresenter's Affiliation: Erasmus Medical Center, Rotterdam, The NetherlandsType of Session: ScientificBackground With the increased use of three-dimensional conformal radiotherapy (3D-CRT) and intensity...
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