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Abramson Cancer CenterSunday, June 1 , 2008
OncoLink reporters provide in-depth coverage of scientific presentations from the 44th Annual ASCO Meeting.
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A Phase II multicenter, randomized trial to compare anastrazole plus gefitinib with anastrazole plus placebo in postmenopausal women with hormone receptor-positive (HR+) metastatic breast cancer (MBC)
Presenter: M. CristofanilliPresenter's Affiliation: MD Anderson Cancer CenterType of Session: ScientificBackground It is well known that hormonal receptor status is an important prognostic factor in metastatic breast cancer patients and has... |
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A randomized phase III trial of four cisplatin (CIS) containing doublet combinations in stage IVB, recurrent, or persistent cervical carcinoma: A Gynecologic Oncology Group (GOG) study
Presenter: B. J. MonkPresenter's Affiliation: University of California, Irvine, Orange, CAType of Session: ScientificBackground Cervical cancer represents the third most common gynecologic malignancy in the United States. Although... |
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A randomized phase III trial of four cisplatin (CIS)- containing doublet combinations in stage IVB, recurrent, or persistent cervical carcinoma: A Gynecologic Oncology Group (GOG) study
A randomized phase III trial of four cisplatin (CIS)- containing doublet combinations in stage IVB, recurrent, or persistent cervical carcinoma: A Gynecologic Oncology Group (GOG) study Several studies have demonstrated varying degrees of benefit... |
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Adjuvant ovarian suppression combined with tamoxifen or anastrazole, alone or in combination with zoledronic acid, in premenopausal women with endocrine-responsive, stage I and II breast cancer: First efficacy results from ABCSG
Presenter: M. GnantPresenter's Affiliation: Medical University of ViennaType of Session: ScientificBackground In hormone receptor-positive breast cancers, growth of the tumor is stimulated by estrogens. Decreasing the production of... |
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FLEX: A randomized,multicenter, phase III study of cetuximab in combination with cisplatin/ vinorelbine (CV) versus CV alone in the first-line treatment of patients with advanced non-small cell lung cancer (NSCLC)
Presenter: R. PirkerPresenter's Affiliation: Medical University of Vienna, Vienna, AustriaType of Session: PlenaryBackground Lung cancer represents the most common cause of cancer death in both men and women in the United States. Non-small... |
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FLEX: A randomized,multicenter, phase III study of cetuximab in combination with cisplatin/ vinorelbine (CV) versus CV alone in the first-line treatment of patients with advanced non-small cell lung cancer (NSCLC)
FLEX: A randomized,multicenter, phase III study of cetuximab in combination with cisplatin/ vinorelbine (CV) versus CV alone in the first-line treatment of patients with advanced non-small cell lung cancer (NSCLC) Epidermal growth factor (EGFR) is... |
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KRAS Status and Efficacy in the First –Line Treatment of Patients with Metastatic Colorectal Cancer (mCRC) Treated with FOLFIRI with or without Cetuximab: The Crystal Experience
KRAS Status and Efficacy in the First –Line Treatment of Patients with Metastatic Colorectal Cancer (mCRC) Treated with FOLFIRI with or without Cetuximab: The Crystal Experience Cetuximab is a targeted therapy agent that blocks epidermal... |
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KRAS Status and Efficacy in the First –Line Treatment of Patients with Metastatic Colorectal Cancer (mCRC) Treated with FOLFIRI with or without Cetuximab: The Crystal Experience
Presenter: Van Cutsem E. Presenter's Affiliation: University Hospital Gasthuisberg, Leuven, Belgium Type of Session: Plenary Background Cetuximab is a chimeric antibody which blocks epidermal growth factor (EGF) signaling by binding to the EGF... |
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Radiotherapy versus carboplatin for Stage I seminoma: Updated analysis of the MRC/EORTC randomized trial (ISRCTN27163214)
Presenter: R. T. OliverPresenter's Affiliation: St. Bartholomew’s Hospital, London, United KingdomType of Session: PlenaryBackground Seminonas are the most common subtype of testicular cancers, accounting for about 40% of cases. Stage I... |
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Radiotherapy versus carboplatin for Stage I seminoma: Updated analysis of the MRC/EORTC randomized trial (ISRCTN27163214)
Radiotherapy versus carboplatin for Stage I seminoma: Updated analysis of the MRC/EORTC randomized trial (ISRCTN27163214) Seminoma (the most common type of testicular cancer) has traditionally been treated with orchiectomy followed by radiation... |
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Randomised, double-blind, placebo controlled, phase III study of bevacizumab (BV) with docetaxel (D) or docetaxel with placebo (PL) as first line therapy for patients with locally recurrent or metastatic breast cancer (mBC): AVADO
Presenter: David Miles, MDPresenter's Affiliation: Mount Vernon Cancer Center, UKType of Session: ScientificBackground Bevacizumab (BV) is a monoclonal antibody to VEGF that inhibits angiogenenesis, and therefore prevents tumor growth. It... |
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Randomised, double-blind, placebo controlled, phase III study of bevacizumab (BV) with docetaxel (D) or docetaxel with placebo (PL) as first line therapy for patients with locally recurrent or metastatic breast cancer (mBC): AVADO
Randomised, double-blind, placebo controlled, phase III study of bevacizumab (BV) with docetaxel (D) or docetaxel with placebo (PL) as first line therapy for patients with locally recurrent or metastatic breast cancer (mBC): AVADO Bevacizumab is a... |
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Randomized Trial of Standard Versus Higher Dose Prophylactic Cranial Irradiation (PCI) in Limited Stage Small Cell Lung Cancer (SCLC) Complete Responders (CR): Primary End Point Analysis (PCI99-01, EORTC 22003-08004, RTOG 0212)
Presenter: Le Pechoux C.Presenter's Affiliation: Institute Gustav Roussy, Villejuif, FranceType of Session: ScientificBackground The use of prophylactic cranial irradiation (PCI) in patients with limited stage small cell lung cancer (SCLC) has... |
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Randomized Trial of Standard Versus Higher Dose Prophylactic Cranial Irradiation (PCI) in Limited Stage Small Cell Lung Cancer (SCLC) Complete Responders (CR): Primary End Point Analysis (PCI99-01, EORTC 22003-08004, RTOG 0212)
Randomized Trial of Standard Versus Higher Dose Prophylactic Cranial Irradiation (PCI) in Limited Stage Small Cell Lung Cancer (SCLC) Complete Responders (CR): Primary End Point Analysis (PCI99-01, EORTC 22003-08004, RTOG 0212) The use of... |
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Sentinel Lymph Node Biopsy Improves Survival Among SEER Patients with Melanoma
Presenter: Gimotty P. Presenter's Affiliation: University of Pennsylvania Type of Session: Scientific Background Regional lymph node metastases increase the risk of melanoma-specific death. Sentinel lymph node biopsy (SLNB) provides... |
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SO124: A Randomized Phase III Trial Comparing Irinotecan/Cisplatin (IP) with Etoposide/Cisplatin (EP) in Patients (pts) with Previously Untreated Extensive Stage Small Cell Lung Cancer (E-SCLC)
Presenter: Natale R.B.Presenter's Affiliation: Cedar Sinai Cancer Center, Los Angeles, CaliforniaType of Session: ScientificBackground The most widely accepted standard of care for small call lung cancer (SCLC) for the past 20 years has been... |
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SO124: A Randomized Phase III Trial Comparing Irinotecan/Cisplatin (IP) with Etoposide/Cisplatin (EP) in Patients (pts) with Previously Untreated Extensive Stage Small Cell Lung Cancer (E-SCLC)
SO124: A Randomized Phase III Trial Comparing Irinotecan/Cisplatin (IP) with Etoposide/Cisplatin (EP) in Patients (pts) with Previously Untreated Extensive Stage Small Cell Lung Cancer (E-SCLC) The combination of etoposide and cisplatin (EP) is the... |
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Vaginal brachytherapy versus external beam pelvic radiotherapy for high-intermediate risk endometrial cancer: Results of the randomized PORTEC-2 trial
Presenter: R.A. NoutPresenter's Affiliation: Leiden University Medical Center, Leiden, NetherlandsType of Session: ScientificBackground Endometrial carcinoma represents the most common gynecologic malignancy in the United States, and the second... |
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