OncoLink at ASTRO 2010

Coverage of the 2010 annual meeting of the American Society for Therapeutic Radiology And Oncology, ASTRO, held in San Diego, CA.

10-year results of Adjuvant Radiotherapy after Radical Prostatectomy in pT3N0 Prostate Cancer Authors: M. Bolla1, H. Van Poppel2, B. Tombal3, K. Vekemans4, L. Da Pozzo5, T. M. De Reijke6, A. Verbaeys7, J. F. Bosset8, R. Van Velthoven9, L. Collette10 Institution: 1 CHU de Grenoble - A Michallon, Grenoble, France 2 Leuven University...
A Dose-response Relationship for the Incidence of Radiation-related Heart Disease Authors: S. C. Darby, D. Brønnum, C. Correa, M. Ewertz, G. Gagliardi, B. Gigante, P. McGale, A. Nisbet, C. Taylor, P. Hall. Affiliations: University of Oxford, Oxford, United Kingdom. Aalborg Hospital, Aalborg, Denmark. University of Odense, Odense,...
A Phase II Trial of Stereotactic Body Radiation Therapy for Operable T1N0M0 Non-small Cell Lung Cancer: Japan Clinical Oncology Group (JCOG0403) Authors: Y. Nagata, M. Hiraoka, T. Shibata, H. Onishi, M. Kokubo, K. Karasawa, Y. Shioyama, R. Onimaru, E. Kunieda, S. Ishikura Institution: Hiroshima University,, Hiroshima, Japan, Kyoto University, Kyoto, Japan, JCOG Data Center, National Cancer...
An Updated Report on the Pathologic Complete Response and Survival Outcome of Southwest Oncology Group (SWOG S0536): A Phase II Trial of Oxaliplatin (oxp) Plus Protracted Infusion 5-Fluorouracil (PIFU) and External Beam Radiation (EBRT) Prior to Surgery for Potentially Curable Esophageal Adenocarcinoma (EA) with Molecular Correlates Authors: L.P. Leichman, B. Goldman, C.R. Thomas, K.G. Billingsley, C.L. Corless, H. Lenz, S. Iqbal, J.K. Benedetti, P.J. Gold, C.D. Blanke. Affiliations: Aptium Gastrointestinal Cancer Consortium. Palm Springs, CA. Southwest Oncology Group....
Brain Metastases from Breast Cancer: Recursive Partitioning Analysis of Prognostic Factors Including Molecular Subtypes and Treatment Authors: R. Le Scodan, C. Massard, L. Jouanneau, F. Coussy, M. Gutierrez, Y. Kirova, A. Labib, E. Mouret-Fourme Institution: Institut Curie, Hopital Rene Huguenin, Saint Cloud, France; Institut Gustave Roussy, Villejuif, France; Institut Curie,...
Carbon Ion Radiotherapy for Primary Malignant Bone Tumors of the Sacrum Authors: T. Kamada, R. Imai, H. Tsuji, T. Imaizumi, H. Tsujii Institution: National Institute of Radiological Sciences, Chiba, Japan Background Primary malignant bone tumors of the sacrum are extremely rare, and their management complex...
Comparison of Health-related Quality of Life 5 Years after Brachytherapy (BT) or Radical Prostatectomy (RP): The SPIRIT (Surgical Prostatectomy vs. Interstitial Radiotherapy Intervention Trial) Cohort (ACOSOG Z0070) Authors: J. M. Crook, A. Gomez-Iturriaga, K. Wallace, S. Fung, S. Alibhai, M. Jewett, N. Fleshner Institutions: University of British Columbia, Kelowna, BC, Canada; Cruces Hospital, Barakaldo, Spain; Princess Margaret Hospital, Toronto, ON,...
Five Year Results of US Intergroup/RTOG 9704 with Postoperative Ca 19-9 #90 and Comparison to the Conko-001 Trial Authors: A. C. Berger1,K. Winter2,J. P. Hoffman3,W. F. Regine4,R. A. Abrams5,H. Safran6,G. M. Freedman3,A. B. Benson7,J. MacDonald8,C. Willet9 Institution: 1 Thomas Jefferson University, Philadelphia, PA 2 Radiation Therapy Oncology Group,...
Gamma Knife Radiosurgery (GKRS) in the Management of Parkinson's Disease and Essential Tremor: Long-term Follow-up Report of 192 Cases Authors: C. Frentress, R.J Mark, H. Smith, D. Jacques, R. Young, B. Copcutt, C. Chen, P.J. Anderson, M. Nair. Background Tremor secondary to Parkinson's disease (PD) and Essential Tremor (ET) are often progressive in nature and without effective...
Hematologic Toxicity on RTOG 0418: A Phase II Study of Post-operative IMRT for Gynecologic Cancer Authors: A. H. Klopp1, J. Moughan2, L. Portelance3, B. E. Miller4, M. R. Salehpour1, D. D'Souza5, L. Souhami3, W. Small6, R. Gaur7, A. Jhingran1 Institution: 1 M.D. Anderson Cancer Center, Houston, TX 2 RTOG Statistical Center,...
High-dose, Spot Scanning Based Proton Therapy For Paraspinal / Retroperitoneal Neoplasms and Small Bowel Tolerance: Dose Distribution Analysis in a Patient Cohort Authors: R. A. Schneider, V. Vitolo, F. Albertini, T. Koch, C. Ares, A. Lomax, G. Goitein, E. B. Hug. Affiliations: Paul Scherrer Institute, Villigen PSI, Switzerland. Fondazione CNAO, Pavia, Italy. University of Zurich, Zurich, Switzerland. ...
Initial Report of RTOG 9601: A Phase III Trial in Prostate Cancer: Anti-androgen Therapy (AAT) with Bicalutamide during and after Radiation Therapy (RT) Improves Freedom from Progression and Reduces the Incidence of Metastatic Disease in Patients following Radical Prostatectomy (RP) with pT2-3, N0 Disease, and Elevated PSA Level Authors: W.U. Shipley, D. Hunt, H. Lukka, P. Major, N.M. Heney, D. Grignon, M. Patel, J. Bahary, C. Lawton, H. Sandler. Affiliations: Massachusetts General Hospital. Boston MA. RTOG Statistical Center. Philadelphia, PA. Mcmaster University...
Initial Report of UCCRC 3443: A Prospective Study on the Utility of Magnetic Resonance Imaging (MRI) in Determining Candidacy for Partial Breast Irradiation (PBI) Authors: P.L. Dorn, H. Al-Hallaq, M. Goldberg, Y. Hassan, N. Jaskowiak, G. Newstead, S.J. Chmura. Background For several decades, whole breast irradiation (WBI) has been used after breast conserving surgery as a means of reducing risk of...
Intensified Chemotherapy and Dose-Reduced Involved Field Radiotherapy in Patients with Early Unfavorable Hodgkin Lymphoma: Final Analysis of the German Hodgkin Study Group (GHSG) Randomized HD11 Trial Authors: H. T. Eich, R. P. Mueller, V. Diehl, H. Gorgen, H. Mueller-Hermelink, B. Schmidt, Grosu, J. Karstens, N. Willich, A. Engert Institutions: Department of Radiation Oncology, University of Cologne, Cologne, Germany; Clinic for Internal...
Intergroup Randomized Phase 3 Study of Androgen Deprivation Therapy (ADT) + Radiation Therapy (RT) in Locally Advanced Prostate Cancer (CaP) (NCIC-CTG, SWOG, MRC-UK, and INT: T94-0110; NCT00002633) Authors: M.D. Mason, P.R. Warde, M.R. Sydes, M.K. Gospodarowicz, G.P. Swanson, P. Kirkbride, E. Kostashuk, J. Hetherington, K. Ding, W. Parulekar Affiliations: Cardiff University. Cardiff, UK. Princess Margaret Hospital and University of Toronto....
Long-term Survival and Competing Causes of Death in Men with Stage I Seminoma Authors: C. J. Beard, M. Chen, N. D. Arvold, P. L. Nguyen, A. K. Ng, K. E. Hoffman Institutions: Dana-Farber Cancer Institute, Boston, MA; University of Connecticut, Storrs, CT; Harvard Radiation Oncology Program, Boston, MA; The University of...
Outcome of Radiotherapy Alone in HPV Associated Oropharyngeal Cancer Authors: B. O'Sullivan, S. Huang, B. Perez-Ordonez, F. Liu, C. Massey, I. Weinreb, E. Chen, B. Cummings, J. Kim, J. Waldron Affiliations: Princess Margaret Hospital / University of Toronto, Toronto, ON, Canada Background There is a growing...
Patient Reported Cosmetic Outcomes and Complications after Breast Conserving Treatment Authors: C. E. Hill-Kayser, C. Vachani, M. K. Hampshire, G. A. Di Lullo, J. M. Metz Institution: University of Pennsylvania Medical Center, Philadelphia, PA Background Over the past 30 years, much work in treatment of breast cancer has...
Patterns of Radiotherapy Practice for Patients Treated for Intact Cervical Cancer in 2005-2007: A QRRO Study Authors: P. J. Eifel1, N. Khalid2, B. Erickson3, C. Crozier2, J. Owen2, J. F. Wilson3 Institution 1 M.D. Anderson Cancer Center, Houston, TX 2 ACR Clinical Research Center, Philadelphia, PA 3 Medical College of Wisconsin, Milwaukee, WI ...
Pelvic Fracture after Radiation Therapy for Localized Prostate Cancer: A Population Based Study Authors: D. M. Housman, C. J. Savage, M. J. Zelefsky, E. B. Elkin Institution: Memorial Sloan-Kettering Cancer Center, New York, NY Background Prostate cancer is the most common malignancy in men; most are diagnosed over age 65, when...
Phase I/II study of Proton-based Short Course Chemoradiation and Early Surgery for Adenocarcinoma of the Pancreas Authors: T. S. Hong, D. P. Ryan, L. S. Blaszkowsky, H. J. Mamon, R. C. Wadlow, E. L. Kwak, C. R. Ferrone, J. Adams, B. Yeap, B. Winrich Institution: Massachusetts General Hospital, Boston, MA; Brigham and Women's Hospital/Dana-Farber Cancer...
Poor Pulmonary Function is not Associated with Increased Rates of Toxicity or Decreased Overall Survival after Stereotactic Body Radiotherapy for Early Stage Non-small Cell Lung Cancer: Results of a Multi-Institutional Analysis Authors: M. Guckenberger1, J. Belderbos2, A. Hope3, L. L. Kestin4, M. Werner-Wasik5, J. J. Sonke2, Y. Xiao5, D. Yan4, J. Wilbert1,I. S. Grills4 Institution: 1Julius-Maximilians University, Wuerzburg, Germany 2The Netherlands Cancer Institute,...
Proton Radiotherapy for Pediatric Medulloblastoma: Improved Early Ototoxicity Authors: B. J. Moeller, M. Chintagumpala, J. J. Philip, S. Y. Woo, J. E. Wolff, A. Mahajan Institution: M.D. Anderson Cancer Center, Houston, TX; Baylor College of Medicine, Houston, TX; University of Louisville School of Medicine, Louisville, KY ...
QRRO 2007 Practice Survey Documents Dramatic Technical Changes in How Radiotherapy for Operable Breast Cancer is Delivered Authors: J.R. White1, N. Khalid2, M.L. Tao3, L.J. Pierce4, A. DeRobertis5, C. Crozier2, J.B. Owen2 and J.F. Wilson1 Institution: 1Medical College of Wisconsin, Milwaukee, WI 2American College of Radiology, Philadelphia, PA 3Epic...
Radiation Induced Rib Fractures after Hypofractionated Stereotactic Body Radiation Therapy: The Risk Factors and Dose-Volume Relationship Authors: K. Asai, Y. Shioyama, S. Ohga, T. Nonoshita, T. Yoshitake, K. Ohnishi, K. Terashima, K. Matsumoto, H. Hirata, H. Honda. Affilations: Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan....
Results of a 2 x 2 Phase III Randomized Trial of Synchronous Chemo-radiotherapy (CRT) Compared to Radiotherapy (RT) Alone and Standard vs. Reduced High Volume RT in Muscle Invasive Bladder Cancer (MIBC) (BC2001 CRUK/01/004) Authors: N. James1, S. Hussain1, E. Hall2, P. Jenkins3, J. Tremlett4, C. Rawlings5, M. Crundwell6, R. Waters2, R. A. Huddart2 Institution: 1 University of Birmingham, Birmingham, United Kingdom 2 Institute of Cancer Research, Sutton,...
Risk Factors Predicting Failure and Prostate Cancer Mortality in High Risk Prostate Cancer Patients Treated with Definitive External Beam Radiation Therapy Authors: Q. Nguyen, L. B. Levy, A. K. Lee, S. Choi, S. J. Frank, K. Hoffman, S. McGuire, D. A. Kuban Institution: M.D. Anderson Cancer Center, Houston, TX Background Prostate cancer is the most common non-cutaneous malignancy in men and is...
RTOG 0229: A Phase II Trial of Neoadjuvant Therapy with Concurrent Chemotherapy and Full Dose Radiotherapy (XRT) followed by Resection and Consolidative Therapy for LA-NSCLC Authors: M. Suntharalingam, R. Paulus, M. J. Edelman, M. Krasna, W. Burrows, E. Gore, S. S. Yom, H. Choy Institution: University of Maryland School of Medicine, Baltimore, MD; RTOG Statistical Center, Philadelphia, PA; University of Maryland...
The Effect of Radiotherapy on Local Regional Recurrence among Patients with Pathologic Complete Response to Neoadjuvant Chemotherapy in Breast Cancer Authors: C. E. Fasola, K. D. Godette, M. W. McDonald, R. M. O'Regan, A. B. Zelnak, J. C. Landry, M. A. Torres. Affiliations: Emory University School of Medicine, Atlanta, GA. Department of Radiation Oncology, Winship Cancer Institute of Emory...
The TME Trial after a Median Follow-up of 11 Years Authors: C. A. Marijnen1, W. van Gijn1, I. D. Nagtegaal2, E. Klein Kranenbarg1, H. Putter1, T. Wiggers3, H. J. T. Rutten4, L. Pahlman5,B. Glimelius5, C. J. H. van de Velde1 Institution: 1 Leiden University Medical Center, Leiden, Netherlands ...
Toxicity of Phase I Radiation Oncology Trials: Worldwide Experience Authors: C. Glass1, R. B. Den2, A. P. Dicker2, Y. R. Lawrence2 Institution: 1 Jefferson Medical College, Philadelphia, PA 2 Department of Radiation Oncology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA ...
Triple-Negative Breast Cancer is Associated with Higher Risk of Local Recurrence after 3D-Conformal External Beam Accelerated Partial Breast Irradiation (3D-APBI) Authors: I. M. Pashtan, M. Ancukiewicz, J. Y.Wo, A. E. Hirsch, B. L. Smith, S. N. Powell, A. Recht, A. G. Taghian. Affiliations: Harvard Radiation Oncology Program, Boston, MA. Massachusetts General Hospital, Boston, MA. Boston Medical Center,...
Two Cycles of ABVD Followed by Involved Field Radiotherapy with 20 Gray (Gy) is the New Standard of Care in the Treatment of Patients with Early Stage Hodgkin Lymphoma: Final Analysis of the Randomized German Hodgkin Study Group (GHSG) Trial HD10 Authors: R. P. Mueller, H. T. Eich, A. Plutschow, J. Debus, M. Bamberg, K. Wilborn, M. Eble, H. Muller-Hermelink, V. Diehl, A. Engert Institutions: Radioonkologie, Klinikum der Universitaet zu Koeln, Koeln, Germany; Medical Oncology, Klinikum der...