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DCIS Hormone Therapy

DCIS Hormone Therapy

Question

Dear OncoLink "Ask The Experts,"

Has any new information come out at recent conferences about the addition of aromatase inhibitors after 2.5 yrs. of Tamoxifen for estrogen-positive DCIS, after a lumpectomy with clear margins? A consultation indicated that it was not necessary in my case. In my research, I find that 5 yrs. of Tamoxifen is considered adequate for DCIS.

Answer

Kevin R. Fox, MD, Assistant Director, Clinical Affairs and Associate Professor of Hematology/Oncology at the Abramson Cancer Center of the University of Pennsylvania, responds:

Your research is correct. The current standard for DCIS is tamoxifen for five years. There is no role for aromotase inhibitors in the treatment of DCIS at this time.