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ESMO: Herceptin Best for HER2+ Breast Cancer Patients

Today - Trastuzumab (Herceptin) is the best drug treatment for human epidermal growth factor receptor 2-positive breast cancer and should remain the standard of care for that type of tumor, according to new research scheduled for presentation at the annual meeting of the European Society of Medical Oncology, held from Sept. 26 to 30 in Madrid.

Low Professional Liability for No Esophageal Cancer Screening

Today - The risk of medical professional liability claims alleging failure to screen for esophageal cancer is not a reason to screen for esophageal cancer, according to a research letter published in the Oct. 1 issue of the Journal of the American Medical Association.


AACR: Dim Light at Night Might Hamper Breast Cancer Therapy

Today - A study in rats hints that exposure to dim light at night may make human breast cancer tumors resistant to doxorubicin. The study was presented at the American Association for Cancer Research's International Conference on Frontiers in Cancer Prevention Research, held from Sept. 28 to Oct. 1 in New Orleans.

ESMO: Combo Treatments Up Survival in Metastatic Melanoma

Sep 30, 2014 - For patients with untreated metastatic melanoma with BRAF V600 mutations, combination treatments of cobimetinib and vemurafenib, and dabrafenib and trametinib, improve progression-free survival. These findings were published online Sept. 29 in the New England Journal of Medicine to coincide with the annual meeting of the European Society of Medical Oncology, held from Sept. 26 to 29 in Madrid.


AACR: Obese in Adolescence, Colon Cancer in Later Life?

Sep 30, 2014 - Obesity and inflammation in late adolescence are associated with increased risk for colon and rectal cancer in adulthood, according to a study presented at the American Association for Cancer Research's International Conference on Frontiers in Cancer Prevention Research, held from Sept. 28 to Oct. 1 in New Orleans.

ESMO: Drug Gives Survival Boost in HER2+ Breast Cancer

Sep 30, 2014 - Adding the drug pertuzumab (Perjeta) to trastuzumab may give women with human epidermal growth factor receptor 2-positive metastatic breast cancer a boost in survival, according to new research presented Sunday at the annual meeting of the European Society of Medical Oncology, held from Sept. 26 to 29 in Madrid.


Oral Sodium Phosphate Doesn't Up Acute Kidney Injury

Sep 29, 2014 - Use of oral sodium phosphate for bowel cleansing prior to a colonoscopy is not associated with the risk of postprocedure acute kidney injury, according to a study published in the September issue of Clinical Gastroenterology and Hepatology.

Higher HDL Cholesterol May Help Protect Against Cancer

Sep 29, 2014 - Higher levels of high-density lipoprotein cholesterol are associated with a decreased risk of cancer among individuals with type 2 diabetes, according to a study published online Sept. 11 in Diabetes Care.


Increasing Skirt Size Tied to Higher Breast Cancer Risk

Sep 26, 2014 - For each increase in skirt size every 10 years, the risk of developing breast cancer after menopause could increase by 33 percent, according to research published online Sept. 24 in BMJ Open.

Lung Infections May Hamper Ability to Detect Lung Cancer

Sep 25, 2014 - A test used to diagnose lung cancer may not be as reliable in geographic regions where certain lung infections are more common, according to research published in the Sept. 24 issue of the Journal of the American Medical Association.


Pancreatic Cancer Risk Not Higher With Diabetes Rx DPP-4i

Sep 24, 2014 - There is no increased short-term pancreatic cancer risk with dipeptidyl-peptidase-4 inhibitors compared to sulfonylureas and thiazolidinediones for glycemic control, according to a study published online Sept. 10 in Diabetes, Obesity and Metabolism.

AACR: Tumor Vulnerability Varies With Clonal Evolution in ALL

Sep 24, 2014 - In acute lymphoblastic leukemia, tumor vulnerability to different chemotherapeutic agents varies at different stages of clonal evolution, which could represent a viable strategy in avoiding drug resistance. These findings were presented at the American Association for Cancer Research's special conference on Hematologic Malignancies: Translating Discoveries to Novel Therapies, held from Sept. 20 to 23 in Philadelphia.


E-Cigarettes Don't Help Cancer Patients Quit Smoking

Sep 24, 2014 - Smokers with cancer who used e-cigarettes along with traditional cigarettes were more dependent on nicotine than those who didn't use the devices, a Memorial Sloan Kettering study found. These patients were also just as likely -- or less likely -- to have quit smoking than patients who didn't use e-cigarettes.

Breast Cancer Subtype Affects Survival With Spinal Metastasis

Sep 22, 2014 - For patients with breast cancer with spinal metastases, estrogen receptor/hormone receptor-negative status is associated with worse survival, according to a study published in the Sept. 1 issue of Spine.


Family Squabbles Can Derail Recovery From Cancer Surgery

Sep 22, 2014 - Cancer patients burdened by stress and family conflicts before surgery may face a higher risk for complications following their operation, according to a study published in a recent issue of the Journal of Gastrointestinal Surgery.

Wild Berry May Boost Effect of Chemo for Pancreatic Cancer

Sep 19, 2014 - The use of micronutrients such as chokeberry extract may augment the cytotoxic effects of chemotherapy drugs on cancer cells, according to research published online Sept. 17 in the Journal of Clinical Pathology.


ASTRO Issues Second List of Choosing Wisely Guidelines

Sep 19, 2014 - The American Society for Radiation Oncology has released a second list of five radiation oncology-specific treatments that should be discussed before being prescribed, as part of the national Choosing Wisely campaign.

PET-CT Prognostic After Induction Tx in Follicular Lymphoma

Sep 19, 2014 - The five-point Deauville scale, used to score 18F-fluorodeoxyglucose (FDG) uptake on FDG positron emission tomography-computed tomography scans, has prognostic value in follicular lymphoma, according to a study published online Sept. 18 in The Lancet Haematology.


AACR: New Drug May Add to Therapy for Head and Neck CA

Sep 19, 2014 - The investigational drug alpelisib (previously known as BYL719) appears to inhibit activation of the pathway that leads to resistance to cetuximab, an anti-epidermal growth factor receptor agent used in the treatment of head and neck cancer. These findings were presented at the American Association for Cancer Research's special conference "Targeting the PI3K-mTOR Network in Cancer," held from Sept. 14 to 17 in Philadelphia.



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