Thursday, December 6, 2012 (Last Updated: 12/07/2012)
Aisyah Mohd Noor, M.D., of King's College London, and colleagues used data from 10,784 incident cases to examine the effect of patient socioeconomic status on access to early-phase cancer trials.
The researchers found that 430 patients were referred to an early-phase oncology trials unit. Patients in the more-deprived quintiles were significantly less likely to be referred compared with patients in the less-deprived quintiles (odds ratio, 0.53). After review in the unit, trial enrollment was not affected by socioeconomic status. Non-white patients were significantly less likely to be recruited (odds ratio, 0.48), but after adjustment for age, gender, cancer type, and deprivation index, the association did not persist.
"The least-deprived patients are almost twice as likely to be referred compared with the most deprived," the authors write. "This may be because more-deprived patients are less suitable for a trial -- as a result of comorbidities, for example -- or because of inequalities that could be addressed by patient or referrer education. Once reviewed at the unit, enrollment onto a trial is not affected by deprivation."
Hematology & Oncology
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