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FDA: Gleevec's Latest Approval Is for Pediatric Cancer

Friday, January 25, 2013 (Last Updated: 01/28/2013)

FRIDAY, Jan. 25 (HealthDay News) -- The anti-cancer drug Gleevec (imatinib) has received new U.S. Food and Drug Administration approval to treat children newly diagnosed with Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia (ALL), the agency said Friday.

Ph+ ALL progresses rapidly if left untreated. Gleevec, among a class of drugs called tyrosine kinase inhibitors, blocks proteins that promote development of cancer cells, the FDA said in a news release.

The most common side effects observed in pediatric testing included infection and a decrease in white blood cells and blood platelets.

Gleevec was first approved in 2001 to treat a form of chronic myeloid leukemia, and has since been approved to treat several other conditions. The drug is marketed by Novartis, based in East Hanover, N.J.

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Specialties Internal Medicine
Family Practice
Hematology & Oncology
Pathology
Pharmacy
OBGYN & Women's Health
Nursing

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