Cancer that starts in the brain is called a primary brain tumor. There are many types of brain tumors, each with a unique prognosis and treatment.
Brain Tumors versus Brain Metastases Differing between these two types of brain lesions is a common source of confusion for many people. Primary brain tumors are tumors that start in the brain, and are actually quite rare, with an estimated 22,020 new cases in 2010. Brain metastases, commonly called "brain mets" are far more common, and are tumors that have traveled to the brain from another area of the body. It is estimated that between 100,000-170,000 patients develop brain metastases each year. Let's use an example to better understand this latter concept: a lung cancer is first formed in the lung tissue, but tumor cells can break off from the original mass and travel through the bloodstream or lymph system to other areas of the body, including the brain. This spreading of the tumor is known as "metastasis". When a lung cancer metastasizes to the brain, this "brain tumor" is ... read more on Brain Metastases and Available Treatments
Clarification of the jargon The term “brain cancer“ is commonly used, but can be a confusing term, as it makes all brain cancers sound like one type of cancer. Brain cancer as a term actually encompasses a variety of cancers. There are tumors which arise from the brain itself, known as primary brain cancers, and of which there are several. There are also brain metastases, which represent the spread of other cancers, such as lung or breast, to the brain. Please refer to the Overview of Brain Metastases for more information on that type of brain cancer. What is the brain? The brain is the organ in a person's skull that controls the functions of all of the other organs. Together, the brain and spine make up the central nervous system. The brain is responsible for the experience of the five senses (taste, touch, sight, hearing and smell). The brain is also the seat of thought, language, ... read more on Brain Cancer: The Basics
FAQs about brain tumors, answered by experts in the field.
Hereditary Brain Cancer and Glioblastoma Multiforme
Dear OncoLink, My mother has recently been diagnosed as having a glioblastoma. I wonder if you could suggest a source for information regarding genetic causes. I had an uncle die from the same tumor eight months ago. Can you make any suggestions? With Kind Regards, DS Nancy J. O'Connor, RN, MSN, CRNP,
Treatment for Optic Nerve Glioma
Dear OncoLink "Ask the Experts," My son has optic nerve glioma of his right eye. His doctor suggested that he should get proton beam therapy. Unfortunately it is not available in my country. Please let you know how this problem can be treated. Thank you in advance. F Eric Shinohara, MD, MSCI Radiation Oncology Section
Treatment for Glioblastoma Multiforme
My friend, aged 38, is suffering from glioblastoma multiforme for the past 2 years. He has undergone surgery, but the cancer in the brain could not be totally removed. Recently, he was diagnosed as having fluid accumulation in the brain and had another operation to remove the fluid. X-ray could not find the tumor anymore. The doctor has
Inspirational articles from patients and survivors.
Essay From Dr. Carl Friedlander, A Brain Cancer Survivor
This document is an attempt on my part to provide people with my view of the history of my past almost four and a half years. During this period I have been dealing with brain cancer and a collection of related drug induced side...
Information about treatment options for brain tumors.
Podcast from Opportunities in Proton Therapy: Chordoma/Chondrosarcoma
Subscribe to OncoLink Podcasts You may also use Quicktime to view the individual presentation: Chordoma/Chondrosarcoma Norbert J. Liebsch, M.D., Ph.D., Assistant Professor of Radiation Oncology, Massachusetts General Hospital Cancer Center,...
Podcast from Opportunities in Proton Therapy: Craniopharyngioma
Subscribe to OncoLink Podcasts You may also use Quicktime to view the individual presentation: Craniopharyngioma Claire Alapetite, M.D, Ph.D., Institut Curie, Radiation Oncology Department, Paris, and Institut Curie Centre de...
News stories related to brain tumors, their diagnosis and treatment.
Reports from professional meetings about brain tumors, their diagnosis and treatment.
Concomitant and adjuvant temozolomide (TMZ) and radiotherapy (RT) for newly diagnosed glioblastoma multiforme (GBM). Conclusive results of a radomized phase III trial by the EORTC Brain & RT Groups and NCIC Clinical Trials Group.
Presenter: R. StuppPresenter's Affiliation: University Hospital (CHUV), Lausanne, SwitzerlandType of Session: PlenaryBackground Glioblastoma multiforme is the most malignant and most common primary brain tumor, with a dismal median overall survival of less than one year. Radiation treatment has long been the standard of care in treating GBM.
Phase III Trial of BCNU Plus Cisplatin (CDDP) Versus BCNU Alone, and Standard Radiation Therapy (SRT) Versus Accelerated Radiation Therapy (ART) in Glioblastoma (GBM) Patients: NCCTG/SWOG Results
Presenter: J.C. Buckner Affiliation: Mayo Clinic, Rochester, MN Background: The adjuvant treatment for GBM is radiation therapy plus or minus BCNU. With this therapy, the median survival is about 10 months and the 5- year overall survival is about 1%. With such poor outcomes, new therapeutic approaches are needed. This study was designed
A Multicenter, Randomized, Double Blind, Placebo (PB) Controlled Trial of Marimastat (MT) In Patients with Glioblastoma Multiforme (GBM) or Gliosarcoma (GS) Following Completion of Conventional, First-Line Treatment
Presenter: S. Phuphanich Affiliation: The Marimastat Glioblastoma Study Group Background: The standard adjuvant therapy for GBM is radiation therapy with or without BCNU. The outcomes of therapy for GBM or GS are poor. There is clearly a need for novel treatment approaches. This study looks a Marimastat administration as an attempt to
NCI CANCERLIT® Search: Diagnosis-Histopathology-Pathogenesis of Brain Tumor - October 2001
Neuronal and mixed neuronal glial tumors associated to epilepsy. A heterogeneous and related group of tumours. Cerebral ganglioglioma with epilepsy: neuroimaging features and treatment. Transcranial sonography of brain tumors in the adult:...
NCI CANCERLIT® Search: Diagnosis-Histopathology-Pathogenesis of Brain Tumor - September 2001
Table of ContentsThe c-Jun NH2-terminal kinase3 (JNK3) gene: genomic structure, chromosomal assignment, and loss of expression in brain tumors.Occupational risk factors for brain cancer: a population-based case-control study in Iowa.How could...
NCI CANCERLIT® Search: Therapy of Brain Tumor - October 2001
Temozolomide for malignant brain tumours. Effects of temozolomide in malignant brain tumours. [Postoperative mutism in children with the posterior fossa tumors] The effects of intravenous fentanyl and lidocaine infiltration on the hemodynamic...