What is the Pancreas? The pancreas is a pear-shaped gland, about six inches in length, located deep within the abdomen, between the stomach and the spine. It is referred to in three parts: the widest part is called the head, the middle section is the body, and the thin end is called the tail. The pancreas is responsible for making hormones, including insulin, which help to regulate blood sugar levels, and enzymes, which are used by the bowel for the digestion of food. These enzymes are transported through ducts within the pancreas, emptied into the common bile duct, which carries the enzymes into the bowel. What is Pancreatic Cancer? Pancreatic cancer happens when cells in the pancreas begin to grow uncontrolled, without any "checks and balances." These "out of control" cancer cells then have the ability to spread to nearby lymph nodes and organs (such as the liver ... read more on Pancreatic Cancer: The Basics
News stories relevant to the diagnosis and treatment of pancreatic cancer.
Coverage from professional conferences on research relevant to pancreatic cancer.
Adjuvant Chemoradiation Therapy after Surgical Resection for 1092 Cases of Pancreatic Adenocarcinoma: The Johns Hopkins Hospital - Mayo Clinic Collaborative Study of Pancreatic Cancer
Presenter: C. C. HsuPresenter's Affiliation: Johns Hopkins Hospital, Baltimore, MDType of Session: ScientificBackground Despite aggressive multimodality treatment, pancreatic cancer is associated with a high rate of mortality. Even the 15-20% of patients who present with resectable disease experience 5-year survivals of only 10-25%.
A phase III study of gemcitabine in combination with 5-FU vs. gemcitabine alone in patients with advanced pancreatic carcinoma (E2297): an Eastern Cooperative oncology Group (ECOG) trial
Presenter: J. Berlin Affiliation: ECOG, USA Background: The vast majority of patients with pancreatic cancer are diagnosed with locally advanced unrespectable or advanced disease for which there is no curative therapy. Many chemotherapeutic agents have been evaluated in patients with pancreatic cancer. Gemcitabine (gem) and 5-FU are the
Gemcitabine-Oxaliplatin (GEMOX) combination in advanced pancreatic carcinoma (APC): a Gercor Multicenter phase II study
Presenter: C. Louvet Affiliation: Hospital St-Antoine, Paris France Background: Gemcitabine has been shown to be an active agent in the treatment of pancreatic cancer. Some preclinical data showed that the combination of gemcitabine with oxaliplatin (GEMOX) exerts potent antiproliferative effects in human cancer cell lines, including
NCI CANCERLIT® Search: Therapy of Pancreatic Cancer - October 2001
Targeted therapies for killing tumor cells. A proposal of no-touch isolation technique in pancreatoduodenectomy for periampullary carcinomas. Evaluation of gastroenteric bypass for unresectable pancreatic cancer. Modified Devine exclusion for...
NCI CANCERLIT® Search: Therapy of Pancreatic Cancer - September 2001
Table of Contents[Laparoscopic left pancreas resection in tumors. Initial clinical experiences][Surgical palliation of pancreatic carcinoma. Results of a 7 year period]Gene therapy for pancreatic cancer--current and prospective...
NCI CANCERLIT® Search: Therapy of Pancreatic Cancer - April 2002
Neoadjuvant chemoradiation for localized adenocarcinoma of the pancreas: great logic, grim reality. Neoadjuvant chemoradiation for localized adenocarcinoma of the pancreas. Localized adenocarcinoma of the pancreas: the rationale for...