What is hyperpigmentation?

Hyperpigmentation is when your skin, hair, nails, or mucous membranes become darker. It can happen anywhere on your body. The pigment of your skin is made by melanin. The more melanin your body makes, the darker your hair, skin, nails, and mucous membranes will be. Hyperpigmentation can be caused by some types of chemotherapy and radiation therapy. People with darker skin and those treated with both chemotherapy and radiation therapy may have more skin darkening.

Localized (in one area) hyperpigmentation can happen in the veins and skin around an injection site. Other areas it may happen are around your joints, under your fingernails and toenails, and inside your mouth. The causes of these changes are unknown.
Hyperpigmentation caused by radiation therapy is found on the skin within the treatment field. The treated skin may darken and look like a tan. Your skin can also get dry and less stretchy (less elastic). Hyperpigmentation caused by radiation does not go away, although the darkness may lessen over time.

How is it treated?

Hyperpigmentation can be covered with makeup. You can wear longer clothing or get laser therapy. Your care provider will talk about your options with you.

When should I call my care team?

Hyperpigmentation is a cosmetic concern for many people, but it does not affect your health. Talk to your provider about your questions or concerns.