Seroma

Author: OncoLink Team
Last Reviewed: July 26, 2024

What is it?

A seroma is build up of serous fluid (the clear liquid part of blood) after surgery. Seromas usually develop between 7 to 10 days after surgery. They can happen with any surgery but are more likely with breast surgeries such as mastectomy, lumpectomy, and breast reconstruction. A seroma can impact wound healing, cause discomfort, increase the risk of infection, and delay further treatment. There are a number of things that can increase the risk of getting a seroma. These are: 

  • Type of surgery and surgical technique (how the surgery is done). 
  • Amount of drainage from the area after the surgery.
  • Tumor size.
  • Body mass index.
  • Lymph node removal.

How is a seroma managed?

There is no way to completely prevent seromas from happening. During some surgeries, a drain may be placed to collect fluid from the surgical site and will be removed at a later time.

The fluid in a seroma can be removed by putting a very fine needle into the seroma and removing the fluid. This is called a fine-needle aspiration and may need to be done to relieve the seroma. Seromas often go away without treatment. 

When should you call your team?

If you notice a swollen area near the site of a recent surgery or have any new pain, call your provider.  

Kazzam & Ng. Postoperative Seroma Management. 2023.

Boostrom S, Throckmorton A, Boughey J, Holifield A, Zakaria S, Hoskin T, Degnum A. Incidence of clinically significant seroma after breast and axillary surgery. Journal of the American College of Surgeons. 2008:208(1)148-150.

Pogson CJ, Adwani A, Ebbs SR. Seroma Formation following breast cancer surgery. European Journal of Surgical Oncology. 2003:(29)711-717.

NCI Dictionary of Cancer Terms. Found at: https://www.cancer.gov/publications/dictionaries/cancer-terms/def/seroma

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